Mast Cell Tumor in Dogs and Cats

Common info

A mast cell derives from the bone marrow. It can found in the connective tissues, especially vessels and nerves that close to the external surfaces (e.g., skin, lungs, nose, mouth). Their primary responsibilities are to defense against parasitic infections, tissue repair, and reform new blood vessels. The mast cell is also associated with allergic reactions due to various types of chemicals in the cells such as Histamine and Heparin, which help modify the immune system and inflammation. This cancer can found in dogs and some cat breeds, especially in older pets.


The cause of this disease is unknown. It might have to do with genetics, since it’s more common in dogs and some cat breeds such as Boxer, Boston terrier, Blue dog, Pug, Labrador Retriever, Golden Retriever, Weimaraner, Rhodesian ridgeback, Cocker spaniel, Schnauzer, Staffordshire terrier, Beagle, Sharpei. As for cats, often found in Siamese cats. Chronic inflammation is also another cause of the disease.


Mast cell tumors are a type of cancer that occurs in the skin and can also found in other parts of the body. It collects deleterious substances that enter the body, which causes allergy. It later develops itself into a malignant tumor.


  • Vomiting
  • Loss of appetite
  • Diarrhea
  • Pain
  • Itching
  • Lump under the skin

The symptoms found in mast cell in dogs and cats include vomiting, loss of appetite, diarrhea, a lump under the skin, redness and bruising on the skin, lump pain, it can cause itching and inflammation.

Treatment and Prevention

Surgery is essential for treatment. Since tumors are severe and more likely to spread to the nearby areas. In some cases, where surgery cannot perform, radiation may recommend, chemotherapy is also practical. Moreover, Medicines can use to remove tumors as well, such as Prednisolone, Antihistamine, and Antacids.

  1. Vetspecialists | Mast cell tumors in dogs and cats
  2. Vetmed | Mast cell cancer
  3. Wikipedia | Mastocytoma
  4. Wagwalking | Canine mast cell tumors
  5. Honestdocs | Connective tissue tumors in dogs
  6. Petmd | Mast cell tumor (Mastocytoma) in Cats
  7. Petmd | Mast Cell Tumor (Mastocytoma) in Dogs
  8. Macy, D. W. 1985. Canine Mast Cell Tumors. Veterinary Clinics of North America: Small Animal Practice, 15(4), 783–803.
  9. Molander-McCrary, H., Henry, C., Potter, K., Tyler, J., & Buss, M. 1998. Cutaneous mast cell tumors in cats: 32 cases (1991-1994). Journal of the American Animal Hospital Association, 34(4), 281–284.
  10. Patnaik, A. K., Ehler, W. J., & MacEwen, E. G. 1984. Canine Cutaneous Mast Cell Tumor: Morphologic Grading and Survival Time in 83 Dogs. Veterinary Pathology, 21(5), 469–474.
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